Sophos Anti-Virus for Mac OS X. Find your product Version 9. To install Sophos Anti-Virus so that it is managed by Enterprise Console, see the startup guides on the Enterprise Console page. Sophos Anti-Virus for Mac OS X standalone startup guide. Sophos Anti-Virus for Mac OS X Help. Sophos Anti-Virus for Mac OS X release notes. Sophos Central is the unified console for managing all your Sophos products. Sign into your account, take a tour, or start a trial from here.
Is macOS 11 supported?
Yes. Roll-out has successfully completed for Sophos Central and Sophos Enterprise Console (SEC). All customers have received the updated version that supports macOS 11 natively. No customer action is required unless they have devices with M1 processors which require Rosetta 2 to be installed.
Sophos Mac Uninstall

Are M1 Processors supported for macOS 11?
M1 processors are currently supported with Rosetta 2. Customers that have M1 processor devices and are running macOS 11 will need to install Rosetta 2 in order to use Sophos Endpoint products. They do not need to join the early access program.
Rosetta 2 should automatically prompt for installation if it isn’t already in use on the device. If not, manual installation is straightforward. See KBA39501 for further detail.
Sophos Mac Removal Tool

What is Rosetta 2?
Rosetta 2 is a commonly used tool that enables a Mac with Apple silicon to use apps built for a Mac with an Intel processor. For more information, please refer to https://support.apple.com/en-gb/HT211861

Will there be a performance difference when using Rosetta 2?
Native support using the full power and performance of the Apple hardware will always be faster than using Rosetta 2. For normal business users there should not be any discernible difference. For heavy users of disk or CPU (for example: video editing, heavy photoshop usage, compiling) they will notice a difference in performance.
When will M1 processors be natively supported?
An early access program for native Apple M1 processor support is planned to start in April.
Key link: KBA on Big Sur and M1 support